Accepting New Patients - Most Insurance Plans Taken
Transform Your Health with ECS Wellness
At ECS Wellness, we specialize in integrative and holistic medicine, offering personalized cannabis solutions to enhance your well-being. Our compassionate team is dedicated to guiding you on your journey to optimal health.
Balance Your ECS
A Recalibration Station for your Mind, Body, and Spirit.
Let us help you balance your:
Mood Appetite Pain Sleep

The Endocannabinoid System
Endocannabinoid System (ECS) is a complex system in the human body plays a crucial role in regulating various physiological processes, including pain sensation, immune response, and neuroprotection. Cannabinoids interact with this system (primarily through CB1 and CB2 receptors) to exert their effects.
Using the Endocannabinoid System (ECS) as the model, ECS Wellness offers personalized cannabinoid care.
As Integrative Medicine Specialists, we use multiple modalities, such as mind-body medicine, lifestyle medicine, and cannabis therapeutics to help patients re-calibrate and return to homeostasis or balance.
ECS Wellness providers offer prescriptive guidance on how to increase one’s production of endocannabinoids in combination with supplementing with phytocannabinoids from cannabis to achieve an optimal quality of life.
Why ECS Wellness?
Medical Marijuana
We provide access to medical marijuana and expert guidance to patients who qualify and would benefit from the medical benefits of safe cannabinoid therapy.
Holistic Approach
Our specialists integrate mind, body, and spirit through proven techniques, lifestyle medicine, and cannabis therapeutics to create a balanced and effective healing experience.
Expert Guidance
Our knowledgeable healthcare providers offer ongoing support and education throughout your wellness journey.
Patient-Centric Focus
Your health and comfort are our top priorities in every consultation and treatment.
ECS Wellness Advantage
Associated with one of the most prestigious hospital systems in the world, ECS Wellness has the ability to collaborate with MGB and Harvard Medical School Colleagues.
Why Trust Us?
We use NIH-endorsed Patient-Reported Outcome Measures (PROMs)—prestigious tools trusted by leading institutions—to track your symptoms and quality of life, ensuring care aligns with your goals. This patient-first approach drives personalized, evidence-based treatment for better results.

ECS Advantage
As a part of the MGB network, ECS Wellness partners with many departments within the MGB, such as the MGH Neurogastroenterology and MGH Sarcoma Clinics and is proud to be one of the MGH Cancer Center’s Support Services.
Understanding ECS
The Endocannabinoid System (ECS) is your body’s natural balancing mechanism—orchestrating rhythm, tempo, and tone throughout your entire system. More than just regulating sleep, memory, mood, appetite, and pain, the ECS is fundamental to maintaining harmony between mind and body.
Your body produces its own cannabinoids (endocannabinoids) that interact with specialized receptors throughout your nervous system, helping to restore balance when life’s stressors throw you off kilter. This system is designed to return you to your natural state of wellness and ease.
At ECS Wellness, we work with you to optimize your ECS through two primary approaches:
- Increasing your body's own cannabinoid production through mindful activities
- Expert guidance in the use of medical marijuana to regulate your ECS.
Our goal is to help you achieve your optimal ECS wellness —the balanced state where you can experience greater peace, clarity, and well-being in your daily life.

Conditions We Treat
Insomnia
Anxiety
Depression
Chronic Pain
PTSD
Abdominal pain
IBS & IBD
Chronic nausea
cancer related symptoms
Unhealthy Weight
neuropathy
Loss of appetite

ECS Wellness Is Your Gateway to Legal, Safe, Accessible Medical Marijuana
During your consultation, our medical providers will evaluate your condition and create personalized recommendations for your specific diagnosis. These may include medical marijuana alongside holistic approaches such as meditation or nutritional guidance.
If beneficial for your condition, medical marijuana certification will be provided as part of your comprehensive care plan.
Contact ECS Wellness to schedule your consultation and discover how medical marijuana can be integrated into your personalized treatment approach.
Our medical professionals are here to provide guidance, not just a card. We’re committed to helping you understand how cannabis can be most effective for your specific health needs.
Testimonials
EXCELLENT Based on 38 reviews ScottApril 22, 2024Trustindex verifies that the original source of the review is Google. Compassionate, professional, and positive energy. D UmieJanuary 26, 2022Trustindex verifies that the original source of the review is Google. Wonderful & Compassionate!! Heather FMay 21, 2021Trustindex verifies that the original source of the review is Google. Very easy to be honest and yourself when talking to Dr. Zaklin. Jennifer O'ConnellApril 12, 2021Trustindex verifies that the original source of the review is Google. Zaklin is so down to earth and unlike any physician I’ve ever met. He’s honest, listens & gives you the time needed to conquer your goals. His admin Jillian is full of answers & always willing to provide & accommodate any navigation needed to expect the best results for your appointment. His nurses are amazing. Full of education and lead you in the right on Cannabis education & where to purchase product. If I have any questions I know who to call. Don’t think twice about Zaklin Integrative ECS Wellness. They know their stuff! Melissa ReynoldsFebruary 24, 2021Trustindex verifies that the original source of the review is Google. I absolutely love Dr. Zaklin. I am off of my depression medicine with the help of Dr. Z. He is personable and accommodating. I would recommend Dr. Z to everyone. ChristineDecember 18, 2020Trustindex verifies that the original source of the review is Google. So far my experience with Dr. Zaklin and his staff have been really wonderful. I feel like I am in good hands. So refreshing to have a team care and be concerned for your health. A big thank you to Jillian for returning all my phone calls and answering all my questions. jamier gonzalezDecember 11, 2020Trustindex verifies that the original source of the review is Google. I had a great experience at Dc. Ryan Zaklin office, Megan helped me find the right medication and supplements to maintain good health. The staff has been very helpful and very well inform. Sterling McCormickNovember 25, 2020Trustindex verifies that the original source of the review is Google. Dr. Zaklin is refreshing, to say the least. He's very knowledgeable, but he's down to earth and doesn't lord his knowledge over your head. He actually SHARES his knowledge instead. His staff is incredible, too. From the first moment I called the office, I was treated with the utmost friendliness and respect from everyone I talked to. Dr. Z's staff had nothing but good things to say about him, and he had nothing but good things to say about them. That's important to me even as a patient. I like to see that the people who are giving me care are HUMAN BEINGS and that they work as a team. I truly believe I'm being treated, not just my symptoms.
Our Process
Becoming an ECS Wellness Patient
Book A Telemedicine Appointment
Schedule your virtual consultation with our certified cannabis expert.
Complete Patient
Paperwork
Fill out medical history and consent forms through our secure patient portal before your appointment.
Provide Health Insurance Information
Submit insurance information for possible coverage of consultation and complementary holistic services.
Start Your Wellness Journey
Meet with your provider to discuss personalized treatment options and begin your wellness journey.
Latest News - Blog
Read our blogs to stay informed about the latest in cannabinoid medicine.

Surprising Science: How Tylenol and Medical Cannabis Work Through the Same Biological System
Acetaminophen (best known as Tylenol) is one of the most frequently used over-the-counter medications for pain and fever. Yet for decades, the medical community has

New Research Shows Strong Scientific Support for Medical Cannabis in Cancer Care
Major study of 10,000+ papers shows medical cannabis support is much stronger than opposition for cancer care. Learn about this study.

Can Cannabinol (CBN) Improve Breast Cancer Treatment? New Research Says Yes
New research shows cannabinol (CBN) significantly enhances exemestane’s effectiveness against estrogen receptor-positive breast cancer, offering promising potential for improved cancer treatment outcomes.